AP4B1 重组单克隆抗体  84710-3-RR

AP4B1 重组单克隆抗体 84710-3-RR

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  • ¥1500 - 3280
  • Proteintech已认证
  • 84710-3-RR
  • 2025年10月09日
  • WB, IP, ELISA
  • Rabbit
  • human, mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human AP4B1 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      human, mouse

    • 宿主

      Rabbit

    • 应用范围

      WB, IP, ELISA

    • 靶点

      AP4B1

    • 抗体英文名

      AP4B1 Recombinant monoclonal antibody

    • 抗体名

      AP4B1 Recombinant monoclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1500.0
    规格:100ul产品价格:¥2480.0
    规格:150ul产品价格:¥3280.0

    经过测试的应用

    Positive WB detected inMDA-MB-231 cells, MCF-7 cells, HeLa cells, HuH-7 cells, SH-SY5Y cells, NIH/3T3 cells
    Positive IP detected inHeLa cells

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:2000-1:10000
    Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    84710-3-RR targets AP4B1 in WB, IP, ELISA applications and shows reactivity with human, mouse samples.

    经测试应用 WB, IP, ELISA
    经测试反应性 human, mouse
    免疫原

    CatNo: Ag9348

    Product name: Recombinant human AP4B1 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-351 aa of BC014146

    Sequence: MPYLGSEDVVKELKKALCNPHIQADRLRYRNVIQRVIRYMTQGLDMSGVFMEMVKASATVDIVQKKLVYLYMCTYAPLKPDLALLAINTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVAVLGCAKMHNLHGDSEVDGALVNELYSLLRDQDPIVVVNCLRSLEEILKQEGGVVINKPIAHHLLNRMSKLDQWGQAEVLNFLLRYQPRSEEELFDILNLLDSFLKSSSPGVVMGATKLFLILAKMFPHVQTDVLVRVKGPLLAACSSESRELCFVALCHVRQILHSLPGHFSSHYKKFFCSYSEPHYIKLQKVEVLCELVNDENVQQVLEE

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 adaptor-related protein complex 4, beta 1 subunit
    别名 Beta4-adaptin, Beta subunit of AP-4, AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1
    计算分子量 739 aa, 83 kDa
    观测分子量~75 kDa
    GenBank蛋白编号BC014146
    基因名称 AP4B1
    Gene ID (NCBI) 10717
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purfication
    UNIPROT IDQ9Y6B7
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    Adaptor protein (AP) complex is a component of intracellular protein transport. The AP4 complex is involved in sorting transmembrane cargo proteins into transport vesicles for trans-Golgi network export. AP4B1 is a member of the AP4 complex, which also includes AP4E1, AP4M1 and AP4S1. Loss-of-function variants in any of these four members can lead to AP-4-associated hereditary spastic paraplegia (HSP), a neurodegenerative disorder (PMID: 30543385). This antibody recognizes AP4B1.

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