- ￥2800
- Proteintech
- CL594-67890
- 2025年10月09日
- FC (Intra)
- Mouse
- Human, rabbit, mouse, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human HSPB3 protein
- 亚型：
IgG2b
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite®594 Fluorescent Dye
- 适应物种：
Human, rabbit, mouse, rat
- 宿主：
Mouse
- 应用范围：
FC (Intra)
- 靶点：
HSPB3
- 抗体英文名：
CoraLite®594-conjugated HSPB3 Monoclonal antibody
- 抗体名：
CoraLite®594-conjugated HSPB3 Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive FC (Intra) detected in | HeLa cells |
| Positive FC detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension |
| Flow Cytometry (FC) | FC : 0.20 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-67890 targets HSPB3 in FC (Intra) applications and shows reactivity with Human, rabbit, mouse, rat samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | Human, rabbit, mouse, rat |
| 免疫原 |
CatNo: Ag26940 Product name: Recombinant human HSPB3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-130 aa of BC126272 Sequence: MAKIILRHLIEIPVRYQEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAAETPPREGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVEIKDLS |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | heat shock 27kDa protein 3 |
| 别名 | HSPB3, HSPL27, Protein 3, 2A10B5, Heat shock protein beta-3, Heat shock protein family B member 3, HSP 17, HSP27 |
| 计算分子量 | 150 aa, 17 kDa |
| 观测分子量 | 20 kDa |
| GenBank蛋白编号 | BC126272 |
| 基因名称 | HSPB3 |
| Gene ID (NCBI) | 8988 |
| RRID | AB_2923930 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q12988 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Heat shock protein family B (small) member 3 (HSPB3) is the third member of the sHSP family in human and is mainly expressed in skeletal and smooth muscles, and can associate with HSPB2, which is another sHSP prominently expressed in cardiac and skeletal muscles. HSPB3 is involved in several cellular functions such as cell signaling, differentiation, and apoptosis, and mutations of HSPB3 are associated with neuromuscular diseases, such as axonal Charcot‐Marie‐Tooth disease (PMID: 31709619) (PMID: 32093037). The molecular weight of HSPB3 is about 17 kDa.
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