- ￥2800
- Proteintech
- CL594-66818
- 2025年10月09日
- IF/ICC
- Mouse
- human, mouse, rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human ESRRB protein
- 亚型：
IgG1
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite®594 Fluorescent Dye
- 适应物种：
human, mouse, rat
- 宿主：
Mouse
- 应用范围：
IF/ICC
- 靶点：
ESRRB
- 抗体英文名：
CoraLite®594-conjugated ESRRB Monoclonal antibody
- 抗体名：
CoraLite®594-conjugated ESRRB Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | Caco-2 cells |
| Positive FC (Intra) detected in | Caco-2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:300-1:1200 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-66818 targets ESRRB in IF/ICC applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag18626 Product name: Recombinant human ESRRB protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-91 aa of BC131517 Sequence: MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKC |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | estrogen-related receptor beta |
| 别名 | ERR-beta, ERRbeta, ERRB2, ERRb, ERR beta-2 |
| 计算分子量 | 508 aa, 56 kDa |
| 观测分子量 | 47 kDa |
| GenBank蛋白编号 | BC131517 |
| 基因名称 | ESRRB |
| Gene ID (NCBI) | 2103 |
| RRID | AB_3673508 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | O95718 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Estrogen related receptor beta (ESRRB), a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extra embryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta. ESRRB exists various isoforms and molecular weight of each isoform is 48 kDa,55 kDa and 56 kDa.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Anti-Digoxin 产品详情 Dylight 594标记小鼠抗地高辛Digoxin单克隆抗体 Dylight 594-conjugated IgG Fraction Monoclonal Mouse Anti-Digoxin 产品详情
and tissue bioavailability, into synthetic siRNAs. Conferring drug-like properties on siRNAs In exploring the potential of synthetic siRNAs to silence endogenous target genes, we found that chemically stabilized and cholesterol-conjugated siRNAs
Disulfide Conjugation of Peptides to Oligonucleotides and Their Analogs
perchlorate (AnalaR, BDH Chemicals) 2.0 M Tris·Cl, pH 6.8 Formamide (p.a. ≥99.0%, Fluka
技术资料暂无技术资料 索取技术资料
