- ￥3600 - 5000
- Proteintech
- 98194-1-PBS
- 2025年10月09日
- FC (Intra)
- Rabbit
- mouse
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
mouse
- 宿主：
Rabbit
- 应用范围：
FC (Intra)
- 靶点：
CCL3/MIP-1 alpha
- 抗体英文名：
Anti-Mouse CCL3/MIP-1 alpha Rabbit Recombinant Antibody, PBS Only
- 抗体名：
Anti-Mouse CCL3/MIP-1 alpha Rabbit Recombinant Antibody, PBS Only
- 规格：
500ug/1mg
| 规格： | 500ug | 产品价格： | ￥3600.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥5000.0 |
产品信息
98194-1-PBS targets CCL3/MIP-1 alpha in FC (Intra) applications and shows reactivity with mouse samples.
| 经测试应用 | FC (Intra) |
| 经测试反应性 | mouse |
| 免疫原 |
CatNo: Eg2170 Product name: Recombinant Mouse CCL3 protein (rFc Tag) Source: mammalian cells-derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 24-92 aa of NM_011337 Sequence: APYGADTPTACCFSYSRKIPRQFIVDYFETSSLCSQPGVIFLTKRNRQICADSKETWVQEYITDLELNA |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) ligand 3 |
| 别名 | 241695B10, C-C motif chemokine 3, Ccl3, Heparin-binding chemotaxis protein, L2G25B |
| 计算分子量 | 10kd |
| GenBank蛋白编号 | NM_011337 |
| 基因名称 | Ccl3 |
| Gene ID (NCBI) | 20302 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P10855 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Chemokine (C-C motif) ligand 3 (CCL3), also known as MIP-1α, belongs to the family of chemokines. CCL3 has been found in the central nervous system and its cognate receptors, CCR1 and CCR5, have been reported to be expressed by astrocytes, microglia and neurons. CCL3 and its receptors, CCR1 and CCR5, also contribute to the development of bone disease in multiple myeloma by supporting tumor growth and regulating osteoclast differentiation. CCL3 is also associated with the regulation of cell growth, angiogenesis, and metastasis of different tumors such as melanoma, renal cell carcinoma, and colorectal cancer. Moreover, CCL3 enhances cell migration and metastasis by up-regulating matrix metalloproteinase-2 (MMP)-2 expression in chondrosarcoma cells.
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