- ￥5800
- Proteintech
- 66265-1-PBS
- 2025年10月09日
- WB, IHC, IF/ICC, IF-P, Indirect ELISA
- Mouse
- human, mouse, rat, pig
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human GLS protein
- 亚型：
IgG2b
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
human, mouse, rat, pig
- 宿主：
Mouse
- 应用范围：
WB, IHC, IF/ICC, IF-P, Indirect ELISA
- 靶点：
KGA/GAC
- 抗体英文名：
KGA/GAC Monoclonal antibody, PBS Only
- 抗体名：
KGA/GAC Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
66265-1-PBS targets KGA/GAC in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
| 经测试应用 | WB, IHC, IF/ICC, IF-P, Indirect ELISA |
| 经测试反应性 | human, mouse, rat, pig |
| 免疫原 |
CatNo: Ag24227 Product name: Recombinant human GLS protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 370-669 aa of BC038507 Sequence: YVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | glutaminase |
| 别名 | GLS, KGA, 3A12A1, AAD20, EC:3.5.1.2 |
| 计算分子量 | 669 aa, 73 kDa |
| 观测分子量 | 58 kDa, 65 kDa |
| GenBank蛋白编号 | BC038507 |
| 基因名称 | GLS |
| Gene ID (NCBI) | 2744 |
| RRID | AB_2881651 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O94925 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GLS, also named as GLS1 and KIAA0838, belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease(PMID:1672808).The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa)(PMID:12408749). It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase(PMID:447624;7512428). It has 3 isoforms named as KGA, GAM, GAC. This antibody can recognize KGA and GAC.
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