CEP104 多克隆抗体  31847-1-AP

CEP104 多克隆抗体 31847-1-AP

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  • ¥1350 - 3000
  • Proteintech已认证
  • 31847-1-AP
  • 2025年10月09日
  • WB, ELISA
  • Rabbit
  • human
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant human KIAA0562 protein

    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Polyclonal

    • 标记物

      Unconjugated

    • 适应物种

      human

    • 宿主

      Rabbit

    • 应用范围

      WB, ELISA

    • 靶点

      CEP104

    • 抗体英文名

      CEP104 Polyclonal antibody

    • 抗体名

      CEP104 Polyclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1350.0
    规格:100ul产品价格:¥2200.0
    规格:150ul产品价格:¥3000.0

    经过测试的应用

    Positive WB detected inHeLa cells, HepG2 cells, K-562 cells, MOLT-4 cells, SK-BR-3 cells, hTERT-RPE1 cells

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:500-1:2000
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    31847-1-AP targets CEP104 in WB, ELISA applications and shows reactivity with human samples.

    经测试应用 WB, ELISA
    经测试反应性 human
    免疫原

    CatNo: Ag35662

    Product name: Recombinant human KIAA0562 protein

    Source: e coli.-derived, PGEX-4T

    Tag: GST

    Domain: 1-200 aa of NM_014704.3

    Sequence: MPHKIGFVVVSSSGHEDGFSARELMIHAPTVSGWRSPRFCQFPQEIVLQMVERCRIRKLQLLAHQYMISSKIEFYISESLPEYFAPYQAERFRRLGYVSLCDNEKTGCKARELKSVYVDAVGQFLKLIFHQNHVNKYNIYNQVALVAINIIGDPADFSDESNTASREKLIDHYLGHNSEDPALEGTYARKSDYISPLDDL

    宿主/亚型 Rabbit / IgG
    抗体类别 Polyclonal
    产品类型 Antibody
    全称 KIAA0562
    别名 KIAA0562, Centrosomal protein of 104 kDa, Centrosomal Protein 104kDa, Centrosomal Protein 104
    计算分子量104kDa,925aa
    观测分子量70 kDa
    GenBank蛋白编号NM_014704.3
    基因名称 KIAA0562
    Gene ID (NCBI) 9731
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Antigen affinity Purification
    UNIPROT IDO60308
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    KIAA0562, also known as CEP104 (centrosomal protein 104), is a gene encoding a centrosomal protein that is essential for ciliogenesis and the structural integrity of the cilium tip. During ciliogenesis, CEP104 is translocated from the distal tip of the centriole to the elongated cilium tip. CEP104 is expressed in a variety of cell types, including tissues such as testis and kidney. Mutations in its gene are associated with the autosomal recessive disorder Joubert syndrome, which is characterized by distinctive mid-hindbrain and cerebellar malformations, actinic dyskinesia, irregular breathing, developmental delay, and ataxia. In studies, inhibitors of CEP104 such as Cytochalasin D and Vismodegib have been used to investigate their specific role in cellular function.

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