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- 详细信息
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
CoraLite® Plus 555 Fluorescent Dye
- 适应物种:
Human, Non-human primates
- 宿主:
Mouse
- 应用范围:
FC
- 靶点:
CD62P
- 抗体英文名:
CoraLite® Plus 555 Anti-Human CD62P (AK4)
- 抗体名:
CoraLite® Plus 555 Anti-Human CD62P (AK4)
- 规格:
25tests/100tests
| 规格: | 25tests | 产品价格: | ¥920.0 |
|---|---|---|---|
| 规格: | 100tests | 产品价格: | ¥2310.0 |
经过测试的应用
| Positive FC detected in | human peripheral blood platelets |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 5 ul per 10^6 cells in 100 μl suspension |
| This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL555-65164 targets CD62P in FC applications and shows reactivity with Human, Non-human primates samples.
| 经测试应用 | FC |
| 经测试反应性 | Human, Non-human primates |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | selectin P (granule membrane protein 140kDa, antigen CD62) |
| 别名 | CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, SELP |
| 计算分子量 | 830 aa, 91 kDa |
| GenBank蛋白编号 | BC028067 |
| 基因名称 | CD62P |
| Gene ID (NCBI) | 6403 |
| RRID | AB_3084572 |
| 偶联类型 | CoraLite® Plus 555 Fluorescent Dye |
| 最大激发/发射波长 | 554 nm / 570 nm |
| 形式 | Liquid |
| 纯化方式 | Purified by protein-A affinity chromatography |
| UNIPROT ID | P16109 |
| 储存缓冲液 | PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
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