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- 详细信息
- 技术资料
- 免疫原:
Recombinant human SHC1 protein
- 亚型:
IgG2b
- 保存条件:
Store at -80°C.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Mouse
- 应用范围:
WB, Cytometric bead array, Indirect ELISA
- 靶点:
SHC1
- 抗体英文名:
SHC1 Monoclonal antibody, PBS Only (Capture)
- 抗体名:
SHC1 Monoclonal antibody, PBS Only (Capture)
- 规格:
100ug
产品信息
67194-2-PBS targets SHC1 as part of a matched antibody pair:
MP50763-1: 67194-2-PBS capture and 67194-3-PBS detection (validated in Cytometric bead array)
MP50763-3: 67194-2-PBS capture and 67194-4-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | WB, Cytometric bead array, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag25173 Product name: Recombinant human SHC1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-169 aa of NM_183001 Sequence: MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGC |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | SHC (Src homology 2 domain containing) transforming protein 1 |
| 别名 | SHC, 1A5B1, SH2 domain protein C1, SHC transforming protein 1, SHC-transforming protein 1 |
| 计算分子量 | 63 kDa |
| 观测分子量 | 66 kDa |
| GenBank蛋白编号 | NM_183001 |
| 基因名称 | SHC1 |
| Gene ID (NCBI) | 6464 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P29353 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.
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