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- 详细信息
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at 2 - 8°C. Stable for one year after shipment.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
FC
- 靶点:
CEACAM1/3/6 (CD66a/c/d)
- 抗体英文名:
Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit Recombinant Antibody
- 抗体名:
Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit Recombinant Antibody
- 规格:
100ug/500ug/1mg
| 规格: | 100ug | 产品价格: | ¥600.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥2200.0 |
| 规格: | 1mg | 产品价格: | ¥3000.0 |
经过测试的应用
| Positive FC detected in | human peripheral blood leukocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98061-1-RR targets CEACAM1/3/6 (CD66a/c/d) in FC applications and shows reactivity with human samples.
| 经测试应用 | FC |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| 别名 | CD66a/c/d, CD66c, CEACAM3, CEACAM6, CEACAM1 |
| 计算分子量 | 526 aa, 58 kDa |
| GenBank蛋白编号 | BC014473 |
| 基因名称 | CEACAM1 |
| Gene ID (NCBI) | 634 |
| RRID | AB_3672208 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P13688 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2 - 8°C. Stable for one year after shipment. |
背景介绍
CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1/CD66a and can cross-react with CEACAM6/CD66c and CEACAM3/CD66d.
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