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- Proteintech
- 65073-1-Ig
- 2026年02月06日
- FC
- Rat
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2b, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
mouse
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
PD-L1/CD274
- 抗体英文名：
Anti-Mouse PD-L1/CD274 (10F.9G2)
- 抗体名：
Anti-Mouse PD-L1/CD274 (10F.9G2)
- 规格：
500ug
经过测试的应用
| Positive FC detected in | Anti-CD3/CD28 stimulated mouse splenocytes |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65073-1-Ig targets PD-L1/CD274 in IHC, FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | IHC |
| 经测试反应性 | mouse |
| 文献引用反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2b, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD274 antigen |
| 别名 | Cd274, PD-L1, Pdcd1lg1, Pdcd1l1, PD L1 |
| GenBank蛋白编号 | BC066841 |
| 基因名称 | PD-L1 |
| Gene ID (NCBI) | 60533 |
| RRID | AB_3670271 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | Q9EP73 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Programmed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner.
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|---|---|---|
| human | IHC | J Transl Med Immunoproteasome subunits are novel signatures for predicting efficacy of immunotherapy in muscle invasive bladder cancerAuthors - XinJian Wang |
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Purifying and Measuring Immunoglobulin E (IgE) and Anti-IgE
to anaphylaxis. Here, we describe the history behind the IgE discovery and the protocol for purifying IgE and anti-IgE in the mouse. This is followed by our ELISA protocol for mouse IgE detection.
Platelet-associated Ig (PAIg) Elution
OUTLINE Platelet-associated Ig (PAIg) could be eluted from the platelets. As a result of this procedure platelets get destroyed and the eluted Ig is formed of platelet surface-bound Ig and , mainly, of internal
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