K118046P Anti-EFHD1 Polyclonal

The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that， together， form a stable four-helix bundle that enables the binding of calcium ions. Swiprosin-2， also known as EFHD1 (EF-hand domain-containing protein D1)， SWS2， PP3051 or MST133， is a 239 amino acid protein that contains two EF-hand domains and is expressed in a wide variety of tissues， including brain， liver， heart， kidney， testis， ovaries and spleen. Expression of Swiprosin-2， a possible calcium-binding protein， is upregulated during neuronal differentiation， suggesting a role for Swiprosin-2 in brain development and maturation.