- ￥409
- Sigma-Aldrich
- 进口
- 378674-100G
- 2025年09月13日
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- 技术资料
- 保存条件：
常温
- 保质期：
根据瓶身LOT号查询
- 英文名：
Carbendazim
- 库存：
有现货
- 供应商：
浙江羽翔生物科技有限公司
- CAS号：
10605-21-7
- 规格：
100G
属性
质量水平
100
方案
97%
表单
powder
mp
>300 °C (lit.)
溶解性
pyridine: soluble 1%, clear, very faintly brownish-yellow
官能团
amine
SMILES字符串
COC(=O)Nc1nc2ccccc2[nH]1
InChI
1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)
InChI key
TWFZGCMQGLPBSX-UHFFFAOYSA-N
一般描述
应用
- 作为直接接触测定的阳性对照（菌丝体径向生长抑制测定）。
- 作为杀虫剂并研究其对线蚓（Enchytraeus albidus）转录反应的影响
- 作为 广谱抗真菌化合物，用于研究抗结核药物对Dubos肉汤培养基中结核分枝杆jun（ Mycobacterium tuberculosis ）的抑菌作用。
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文献和实验Deleterious effects of benomyl and carbendazim on human placental trophoblast cells.
Benomyl and carbendazim are benzimidazole fungicides that are used throughout the world against a wide range of fungal diseases of agricultural products. There is as yet little information regarding the toxicity of benzimidazole fungicides to human placenta. In this study, we utilized human placental trophoblast cell line HTR-8/SVneo (HTR-8) to access the toxic effects of benomyl and carbendazim. Our data showed that these two fungicides decreased cell viability and the percentages of cells in G0/G1 phase, as well as induced apoptosis of HTR-8 cells. The invasion and migration of HTR-8 cells were significantly inhibited by benomyl and carbendazim. We further found that benomyl and carbendazim altered the expression of protease systems (MMPs/TIPMs and uPA/PAI-1) and adhesion molecules (integrin α5 and β1) in HTR-8 cells. Our present study firstly shows the deleterious effects of benomyl and carbendazim on placental cells and suggests a potential risk of benzimidazole fungicides to human reproduction.
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