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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Histone Deacetylase 5/9.
- 形态:
liquid
- 保存条件:
Store at -20˚C
- 克隆性:
Polyclonal
- 适应物种:
Human;Mouse;Rat
- 保质期:
12 months
- 抗原来源:
Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB, IHC
- 靶点:
Uniprot:Q9UQL6
- 抗体英文名:
Histone Deacetylase 5/9 Antibody
- 规格:
50ul/100ul
计算分子量:124KD
配方:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
应用详情:
Western blotting:1:500 - 1:1000
Immunohistochemistry:1:50 - 1:100
图片:

Western blot analysis of Histone Deacetylase 5/9 expression in mouse muscle (A), rat muscle (B) whole cell lysates.
,

Immunohistochemical analysis of Histone Deacetylase 5/9 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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文献和实验Histone Deacetylase Activity Assay
Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from the ɛ-amino groups of conserved lysine residues in the amino terminal tail of histones. In humans, there are 18 potential deacetylase enzymes
Analysis of Checkpoint Responses to Histone Deacetylase Inhibitors
Cell cycle checkpoints respond to a wide range of stresses to prevent compromise to the integrity of the cell. The best studied checkpoints are those induced by genotoxic agents that cause DNA damage. Histone deacetylase inhibitors
Evaluation of Histone Deacetylase Inhibitors as Therapeutics for Neurodegenerative Diseases
Various neurodegenerative diseases are associated with aberrant gene expression. We recently identified a novel class of pimelic o -aminobenzamide histone deacetylase (HDAC) inhibitors that show promise as therapeutics
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