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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized phosho peptide around human PI3 Kinase Class III (Ser249)
- 形态:
liquid
- 保存条件:
Store at -20˚C
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
12 months
- 抗原来源:
Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 靶点:
Uniprot:Q8NEB9
- 抗体英文名:
PI3 Kinase Class III (phospho-Ser249) rabbit pAb
- 规格:
50ul/100ul
配方:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
应用详情:WB 1:1000-2000
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文献和实验Measurement of Phosphoinositide 3-Kinase Activity
adaptor molecule ( 1 ). The class II PI 3-kinases are characterized by the presence of a C-2 domain at the carboxy terminus and utilize predominantly PtdIns and PtdIns(4)P as substrates (e.g., PI3K-C2α), whereas the class III PI 3-kinases utilize
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
occurs downstream of growth factor and phosphatidylinositol3 kinase (PI3K) signalling. Activation of the canonicalWnt pathway also inhibits GSK3 activity, although this is notmediated by N-terminal phosphorylation but by protein–proteininteractions (9 –
/MTOR 激活类 1)Class III PI3K 结构上类似于Class I PI3K,但作用相反。 接受上述信号的自噬蛋白: 目前都把焦点集中在beclin 1(酵母同源物为atg6),能与多种蛋白结合,如Vps34(Class III PI3K的催化亚单位),mTOR,BCL-2和BCLXL蛋白等,更多介绍请参阅OMIM:http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=604378。
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