- ￥1868
- abinScience
- CHINA
- CB183012
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Dog CD44 Protein, N-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Dog CD44 Protein, N-His |
|---|---|
| Catalog No. | CB183012 |
| Host species | \ |
| Species reactivity | \ |
| Immunogen | \ |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Clonality | \ |
| Isotype | \ |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Target | \ |
| Purification | \ |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | NP_001183951.1 |
| Protein length | Gln21-Thr220 |
| Nature | Recombinant |
| Observed Molecular Weight | \ |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative Names | CD44 antigen precursor; CD44 |
| Clone ID | \ |
| Species | Canis lupus familiaris (Dog) |
| Product Usage Information | \ |
| Note | For research use only |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for ab...
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文献和实验• LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44., PMID:39128424
• Genetic and Epigenetic Regulation of the Innate Immune Response to Gout., PMID:36745138
• CD44 expression identifies astrocyte-restricted precursor cells., PMID:15531362
• Biochemistry of hyaluronan., PMID:3124495
• CD44 and CD27 delineate B-precursor stages with different recombination status and with an uneven distribution in nonmalignant and malignant hematopoiesis., PMID:18005092
• Identification of CD44 as a cell surface marker for Müller glia precursor cells., PMID:20969572
• CD44-positive cells are candidates for astrocyte precursor cells in developing mouse cerebellum., PMID:21732075
• High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL., PMID:39580584
• The CD44 expressed on the earliest intrathymic precursor population functions as a thymus homing molecule but does not bind to hyaluronate., PMID:7507884
吞噬细胞糖蛋白1( CD44) phagocyticglycoproteinl，Pgp-1、Ⅲ型细胞外基质受体(ECMRⅢ)，胞膜外区靠近N端约100个氨基酸范围内有6个半胱氨酸，组成3个二硫键，形成一个球形结构，称连接组件(Linkmodule)，胞膜外区的近膜侧是黏蛋白样区。CD44编码基因转录时可取用不同的外显子，使mRNA水平上出现不同的拼接方式，导致成熟的CIM4分子有几十种变构体，分子质量从80～250kDa不等。人CD44基因含有两类外显
信息 1、Recombinant Gene Expression : Reviews and Protocols Editor(s): Paulina Balbás1, Argelia Lorence2 Affiliation(s): (1),Centro de Investigación en Biotecnología,CuernavacaMéxico (2)Virginia Polytechnic Institute,State University,BlacksburgVA
如下：几丁质结合蛋白域―intein1―MCS―Intein2―几丁质结合蛋白。这个巧妙的设计有3重便利：N-端，C-端或者N-端和C-端同时融合短的内含肽序列。想做N端融合，你可以将目的基因替换MCS―Intein2―几丁质结合蛋白，如果想做C端融合表达，就可以将目的基因替换MCS前面的几丁质结合蛋白域―intein1―MCS，不用分2个载体；而且做过克隆的人会很有体会：很多时候双酶切载体，由于2个酶切位点都多克隆位点上，没有小片断切下来，所以是否成功双酶切就不好判断，如果用Twin载体就会切下一个片断
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