- ￥1868
- abinScience
- CHINA
- ZY457012
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Vicugna pacos IL4 Protein, N-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Vicugna pacos IL4 Protein, N-His |
|---|---|
| Catalog No. | ZY457012 |
| Host species | \ |
| Species reactivity | \ |
| Immunogen | \ |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Clonality | \ |
| Isotype | \ |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Target | \ |
| Purification | \ |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | Q865X5 |
| Protein length | His25-Cys133 |
| Nature | Recombinant |
| Observed Molecular Weight | \ |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative Names | interleukin-4; IL4 |
| Clone ID | \ |
| Species | Vicugna pacos |
| Product Usage Information | \ |
| Note | For research use only |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for ab...
Product categories and application fields.
Main products.
10000+ high-activity proteins.
15000+ antibody series products:
Classic monoclonal antibody.
Monoclonal antibody
Internal control antibody, labeled antibody.
High-quality phosphorylation antibodies.
Highly specific nanobodies and small molecule antibodies.
Functional antibodies in vivo.
Low-background flow cytometry antibodies.
DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验• The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps., PMID:38690264
• Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes., PMID:29930549
• Interleukin 4 and cancer resistance in glioblastoma multiforme., PMID:39164434
• Anti-interleukin-4 therapy., PMID:15474861
• Standardized protocols for differentiation of THP-1 cells to macrophages with distinct M(IFNγ+LPS), M(IL-4) and M(IL-10) phenotypes., PMID:32033786
• Interleukin 4: Its Role in Hypertension, Atherosclerosis, Valvular, and Nonvalvular Cardiovascular Diseases., PMID:31401864
• Interleukin-4-deficient mice., PMID:8303082
• Interleukin 4 inhibition as a potential therapeutic in pemphigus., PMID:26440137
• Interleukin 4., PMID:2262331
偶联受体 (GPCR)，主要表达于免疫源细胞。它涉及炎症、神经退行性疾病、肥胖和疼痛等代谢途径的调节，因此也是药物开发的一个重要靶标。在本篇文章中，作者使用亲和标签开发的新纯化方案能够有效分离宿主细胞中低表达的重组 GPCR。该方法适用于制备毫克量的稳定同位素标记受体，用于高分辨率核磁共振研究。 一、实验设计思路 1、CB2 表达载体构建：为了找到最合适的标签位置，作者对 Linker 和 Twin-Strep-tag 标签位置进行了不同的设计。 2、E.coli 系统表达 CB2 蛋白及膜蛋白制备，测定
Protein表达是一个非常复杂的过程，因此很难预测表达的蛋白是否是可溶性的、包涵体形式还是部分降解的。为了预防各种可能的困难条件，在重组蛋白上导入两种Tag可以提供获得高纯度均质蛋白的灵活性。 蛋白含有两种不同亲和纯化Tag的重要原因： 纯化全长的蛋白 获得最高纯化的蛋白 适合变性或生理条件下纯化 优化的操作过程，可以直接从培养基中纯化蛋白 与Strep-tag®配合最有效的是6xHistidine-tag，总之推荐一个Tag在蛋白的N-端，另外一个Tag在蛋白的C-端。 纯化
Protein表达是一个非常复杂的过程，因此很难预测表达的蛋白是否是可溶性的、包涵体形式还是部分降解的。为了预防各种可能的困难条件，在重组蛋白上导入两种Tag可以提供获得高纯度均质蛋白的灵活性。 蛋白含有两种不同亲和纯化Tag的重要原因： 纯化全长的蛋白 获得最高纯化的蛋白 适合变性或生理条件下纯化 优化的操作过程，可以直接从培养基中纯化蛋白 与Strep
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