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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20° C
- 保质期:
见优宁维官网
- 英文名:
Ubiquitin Activating Enzyme UBE1 (rabbit)
- 库存:
999
- 供应商:
Absin
- 规格:
25ug
产品名:
Ubiquitin Activating Enzyme UBE1 (rabbit)品牌:
Absin货号:
abs42029052保持条件:
Store at -20° C浓度:
见优宁维官网免疫原:
见优宁维官网抗原名称:
见优宁维官网应用:
A biochemical compound that catalyzes the activation of the C-terminal carboxyl group of ubiquitin使用方法:
见优宁维官网产品描述:
UBE1 is responsible for the first step in the ubiquitin-protein isopeptide bond formation. UBE1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high energy thioester bond. This activated ubiquitin is then transferred to the lysine of target proteins via the E2/E3 conjugation cascade. A critical component for the initiation of in vitro conjugation reactions.
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文献和实验Studies of the Ubiquitin Proteasome System
and Purification of Anti‐Ubiquitin Antibodies Support Protocol 3: Preparation of Ubiquitin Affinity Column Generation of Reagent‐Grade Ubiquitin Activating Enzyme (E1) Basic Protocol 20: Preparation of Wheat E1 in E. coli Basic Protocol 21: Preparation of Mouse E1
Stability and Ubiquitination of the Tumor Suppressor Protein p53
-dependent manner through its covalent thio-ester linkage to the E1 ubiquitin-activating enzyme. The activated ubiquitin is then transferred to the E2 enzyme, also known as a ubiquitin conjugating enzyme (UBC), again in the form of a high-energy thio-ester
Purification of E1 and E1-Like Enzymes
Ubiquitin-activating enzyme is the archetype for a family of enzymes catalyzing the ATP-coupled activation of ubiquitin and other class 1 ubiquitin-like proteins required for their subsequent conjugation to cellular targets. The general
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