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- 详细信息
- 技术资料
- 亚型:
IgG1,κ
- 保存条件:
Store at 4℃ in dark.Do not freeze.
- 克隆性:
Monoclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human
- 目录编号:
4907
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Mouse
- 应用范围:
FCM
- 浓度:
FCM 5uL/Test.
- 靶点:
CD73
- 抗体英文名:
Anti-CD73(PE) Monoclonal Antibody
- 规格:
25T/100T
| 规格: | 25T | 产品价格: | ¥2250.0 |
|---|---|---|---|
| 规格: | 100T | 产品价格: | ¥4450.0 |
| 基本信息 | |
| 英文名称 | Anti-CD73(PE) Monoclonal Antibody |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal Antibody |
| 亚型 | IgG1,κ |
| 交叉反应 | Human |
| 应用 | FCM |
| 稀释比例 | FCM 5uL/Test. |
| 密度 | |
| 靶标 | CD73 |
| 别名 | NT5; 5‘ NT; 5‘ nucleotidase (CD73); 5‘ nucleotidase precursor; 5‘ nucleotidase,ecto; 5‘ nucleotidase,ecto (CD73); 5‘-NT; 5‘-nucleotidase; 5‘-nucleotidase; 5NTD_HUMAN; CD73; CD73 antigen; E5NT; Ecto 5‘ nucleotidase; Ecto-5‘-nucleotidase; eN antibody eNT; NT antibody NT5; NT5E; NTE; Purine 5 Prime Nucleotidase |
| 背景说明 | CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins,CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants,yet elicits diverse biological function through differential regulation in endothelial cells (EC),subpopulations of B and T cells,germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts. For example,IgG mediated neutralization of CD73 interferes with lymphocyte adhesion to EC,and blocks aggregation of germinal center B cells and follicular dendritic cells. Furthermore,IgG-mediated targeting of lymphocyte CD73,but not of endothelial cell CD73,causes shedding of CD73 and tyrosine phosphorylation of proteins. |
| Swiss Prot | P21589 |
| Gene ID | 4907 |
| 亚细胞定位 | Cell membrane |
| 储存条件 | Store at 4℃ in dark.Do not freeze. |
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K011106M Anti-CD73(PE) Monoclonal Antibody
¥2250 - 4450








