K113105P Anti-IFITM2/IFITM3/IFITM1/DSPA2d Polyclonal Antibody

K113105P Anti-IFITM2/IFITM3/IF

ITM1/DSPA2d Polyclonal Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K113105P
  • 2025年08月22日
  • IHC
  • Rabbit
  • Human;Mouse;Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human IFITM2/IFITM3/IFITM1/DSPA2d

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Mouse;Rat

    • 抗原来源

      A synthetic peptide of human IFITM2/IFITM3/IFITM1/DSPA2d

    • 目录编号

      10581/10410/8519

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC

    • 浓度

      IHC 1:25-100.

    • 靶点

      IFITM2/IFITM3/IFITM1/DSPA2d

    • 抗体英文名

      Anti-IFITM2/IFITM3/IFITM1/DSPA2d Polyclonal Antibody

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-IFITM2/IFITM3/IFITM1/DSPA2d Polyclonal Antibody
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse;Rat
    应用IHC
    稀释比例IHC 1:25-100.
    密度
    靶标IFITM2/IFITM3/IFITM1/DSPA2d
    别名1 8D; Dispanin subfamily A member 2c; DSPA2c; IFITM 2; Interferon induced transmembrane protein 2 (1 8D); Interferon induced transmembrane protein 2; Interferon inducible protein 1 8D; 9-27; CD 225; CD 225 antigen; CD225; CD225 antigen; Dispanin subfamily A member 2a; DSPA2a; IFI 17; IFI17; IFITM1; IFM1_HUMAN; Interferon induced protein 17; interferon induced transmembrane protein 1 (9-27); Interferon induced transmembrane protein 1; Interferon inducible protein 9-27; Interferon-induced protein 17; Interferon-induced transmembrane protein 1; Interferon-inducible protein 9-27; Leu 13; Leu 13 antigen; Leu-13 antigen; LEU13; 1 8U; Fragilis; IFITM3; IFM3_HUMAN; Interferon induced transmembrane protein 3 (1 8U); Interferon Induced Transmembrane Protein 3; Interferon inducible; Interferon inducible protein 1 8U; Interferon Inducible Protein 15; Interferon Inducible Protein Homolog; Interferon-induced transmembrane protein 3; Interferon-inducible protein 1-8U; IP15;
    背景说明IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2, Marburg virus (MARV, Ebola virus (EBOV, Dengue virus (DNV, West Nile virus (WNV, human immunodeficiency virus type 1 (HIV-1, hepatitis C virus (HCV and vesicular stomatitis virus (VSV. Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV and SARS-CoV-2 S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation. IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome.
    Swiss ProtQ01629/Q01628/P13164/C9JQL5
    Gene ID10581/10410/8519
    亚细胞定位Cell membrane Cytoplasm
    免疫原A synthetic peptide of human IFITM2/IFITM3/IFITM1/DSPA2d
    Public Immunogen Range60-110/132aa
    理论分子量14/15kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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