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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human TAB1
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Mouse
- 抗原来源:
Recombinant protein of human TAB1
- 目录编号:
10454
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
IHC
- 浓度:
IHC 1:50-200.
- 靶点:
TAB1
- 抗体英文名:
Anti-TAB1 Polyclonal Antibody
- 抗体名:
丝裂原激活的蛋白激酶激酶激酶7相互作用蛋白1抗体
- 规格:
20ul/50ul/100ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-TAB1 Polyclonal Antibody |
| 中文名称 | 丝裂原激活的蛋白激酶激酶激酶7相互作用蛋白1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | TAB1 |
| 别名 | 2310012M03Rik;3’-Tab1;MAP3K7IP;1;MAP3K7IP1;MGC57664;Mitogen;activated;protein;kinase;kinase;kinase;7;interacting;protein;1;Mitogen-activated;protein;kinase;kinase;kinase;7-interacting;protein;1;TAB;1;TAB1;TAB1_HUMAN;TAK1;binding;protein;1;TAK1-binding;protein;1;TGF;beta;activated;kinase;1;binding;protein;1;TGF-beta;activated;kinase;1/MAP3K7;binding;protein;1;TGF-beta-activated;kinase;1;and;MAP3K7-binding;protein;1;TGF-beta-activated;kinase;1-binding;protein;1;Transforming;growth;factor;beta;activated;kinase;binding;protein;1; |
| 背景说明 | The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Swiss Prot | Q15750 |
| Gene ID | 10454 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human TAB1 |
| Public Immunogen Range | 130-480aa |
| 理论分子量 | 50/55kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K116858P Anti-TAB1 Polyclonal Antibody
¥480 - 1600









