- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K116814P
- 2025年08月22日
- IHC
- Rabbit
- Human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human ANG
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human
- 抗原来源：
Recombinant protein of human ANG
- 目录编号：
283
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:50-200.
- 靶点：
ANG
- 抗体英文名：
Anti-ANG Polyclonal Antibody
- 抗体名：
血管生成素抗体
- 规格：
20ul/50ul/100ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-ANG Polyclonal Antibody |
| 中文名称 | 血管生成素抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 预测交叉反应 | Bovine;PONTR;Rabbit |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | ANG |
| 别名 | ALS9;AMYOTROPHIC LATERAL SCLEROSIS;ANG 1;ANG;ANG I;ANG1;ANGI;ANGI_HUMAN;Angiogenin;Angiogenin ribonuclease RNase A family; 5;Epididymis luminal protein 168;HEL168;MGC22466;MGC71966;Ribonuclease 5;Ribonuclease RNase A Family 5;RNase 5;RNASE4;RNASE5; |
| 背景说明 | The protein encoded by this gene is a member of the RNase A superfamily though it has relatively weak ribonucleolytic activity. This protein is a potent mediator of new blood vessel formation and thus， in addition to the name RNase5， is commonly called angiogenin. This protein induces angiogenesis after binding to actin on the surface of endothelial cells. This protein also accumulates at the nucleolus where it stimulates ribosomal transcription. Under stress conditions this protein translocates to the cytosol where it hydrolyzes cellular tRNAs and influences protein synthesis. A signal peptide is cleaved from the precursor protein to produce a mature protein which contains a nuclear localization signal， a cell binding motif， and a catalytic domain. This protein has been shown to be both neurotrophic and neuroprotective and the mature protein has antimicrobial activity against some bacteria and fungi， including S. pneumoniae and C. albicans. Due to its effect on rRNA production and angiogenesis this gene plays important roles in cell growth and tumor progression. Mutations in this gene are associated with progression of amyotrophic lateral sclerosis (ALS). This gene and the neighboring RNase4 gene share promoters and 5’ exons though each gene then splices to a distinct 3’ exon containing the complete coding region of each gene. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Swiss Prot | P03950 |
| Gene ID | 283 |
| 亚细胞定位 | Secreted |
| 免疫原 | Recombinant protein of human ANG |
| Public Immunogen Range | 25-148aa |
| 理论分子量 | 17kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K116814P Anti-ANG Polyclonal Antibody
￥480 - 1600
