- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K116025P
- 2025年08月22日
- WB
- Rabbit
- Human
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- 详细信息
- 技术资料
- 免疫原：
A synthetic peptide of human CD19
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human
- 抗原来源：
A synthetic peptide of human CD19
- 目录编号：
930
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
WB 1:1000-3000.
- 靶点：
CD19
- 抗体英文名：
Anti-CD19 Polyclonal Antibody
- 抗体名：
CD19抗体
- 规格：
50ul/100ul/20ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 20ul | 产品价格： | ￥480.0 |
| 基本信息 | |
| 英文名称 | Anti-CD19 Polyclonal Antibody |
| 中文名称 | CD19抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human |
| 预测交叉反应 | Monkey(100%) |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | CD19 |
| 别名 | B lymphocyte antigen CD19; CD19 molecule; CD19 antigen; Differentiation antigen CD19; Ig kappa chain V-I region HK101; IGKC; Immunoglobulin kappa constant; immunoglobulin kappa light chain; |
| 背景说明 | This gene encodes a member of the immunoglobulin gene superfamily. Expression of this cell surface protein is restricted to B cell lymphocytes. This protein is a reliable marker for pre-B cells but its expression diminishes during terminal B cell differentiation in antibody secreting plasma cells. The protein has two N-terminal extracellular Ig-like domains separated by a non-Ig-like domain， a hydrophobic transmembrane domain， and a large C-terminal cytoplasmic domain. This protein forms a complex with several membrane proteins including complement receptor type 2 (CD21) and tetraspanin (CD81) and this complex reduces the threshold for antigen-initiated B cell activation. Activation of this B-cell antigen receptor complex activates the phosphatidylinositol 3-kinase signalling pathway and the subsequent release of intracellular stores of calcium ions. This protein is a target of chimeric antigen receptor (CAR) T-cells used in the treatment of lymphoblastic leukemia. Mutations in this gene are associated with the disease common variable immunodeficiency 3 (CVID3) which results in a failure of B-cell differentiation and impaired secretion of immunoglobulins. CVID3 is characterized by hypogammaglobulinemia， an inability to mount an antibody response to antigen， and recurrent bacterial infections. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Swiss Prot | P15391 |
| Gene ID | 930 |
| 亚细胞定位 | Cell membrane |
| 免疫原 | A synthetic peptide of human CD19 |
| Public Immunogen Range | 506-556/556aa |
| 理论分子量 | 61kDa |
| 实际分子量 | 95kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K116025P Anti-CD19 Polyclonal Antibody
￥480 - 1600
