K010492P Anti-GJB6 Polyclonal Antibody

K010492P Anti-GJB6 Polyclonal

Antibody
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  • ¥3300
  • Solarbio|ActivAb
  • 北京
  • K010492P
  • 2025年08月22日
  • Rabbit
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human GJB6

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 抗原来源

      A synthetic peptide of human GJB6

    • 目录编号

      10804

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 浓度

      WB 1:500-2000.IHC 1:50-200.IF 1:100-500.

    • 靶点

      GJB6

    • 抗体英文名

      Anti-GJB6 Polyclonal Antibody

    • 抗体名

      间隙连接蛋白30/GJB6抗体

    • 规格

      100ul

    基本信息
    英文名称Anti-GJB6 Polyclonal Antibody
    中文名称间隙连接蛋白30/GJB6抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    稀释比例WB 1:500-2000.IHC 1:50-200.IF 1:100-500.
    密度
    靶标GJB6
    别名Connexin 30; Connexin-30; Cx30; CXB6_HUMAN; DFNA3; DFNA3B; DFNB1B; ECTD2; ectodermal dysplasia 2, hidrotic (Clouston syndrome); ED2; EDH; Gap junction beta 6 protein; Gap junction beta-6 protein; gap junction protein, beta 6 (connexin 30); gap junction protein, beta 6; Gap junction protein, beta 6, 30kDa; GJB6; HED; HED2; NSRD1;
    背景说明The connexin family of proteins form hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences between connexins arise from specific amino-acid substitutions in the most highly conserved domains: the transmembrane and extracellular regions. Connexin 30, also known as GJB6 (Gap junction beta 6), ED2, EDH, HED or DFNA3, is a 261 amino acid multi-pass membrane protein that localizes to the cell junction and belongs to the connexin family. Functioning as a hexamer with other connexin proteins, connexin 30 facilitates the diffusion of low molecular weight materials from one cell to another. Defects in the gene encoding connexin 30 are the cause of ectodermal dysplasia type 2 (ED2) and non-syndromatic sensorineural deafness autosomal dominant type 3 (DFNA3), the former of which is characterized by abnormal development of ectodermal structures (such as skin and nails).
    Swiss ProtO95452
    Gene ID10804
    亚细胞定位Cell membrane
    免疫原A synthetic peptide of human GJB6
    理论分子量29 kDa
    EC
    纯化方法Affinity purification
    储存液Rabbit IgG in phosphate buffered saline,pH 7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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