K115034P Anti-RNF114 Polyclonal Antibody

K115034P Anti-RNF114 Polyclona

l Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K115034P
  • 2025年08月22日
  • IHC;WB
  • Rabbit
  • Human;Rat;Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human RNF114

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Rat;Mouse

    • 抗原来源

      Recombinant protein of human RNF114

    • 目录编号

      55905

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC;WB

    • 浓度

      WB 1:1000-3000.IHC 1:50-200.

    • 靶点

      RNF114

    • 抗体英文名

      Anti-RNF114 Polyclonal Antibody

    • 抗体名

      无名指蛋白114

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-RNF114 Polyclonal Antibody
    中文名称无名指蛋白114
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Rat;Mouse
    预测交叉反应Pig;Bovine
    应用IHC;WB
    稀释比例WB 1:1000-3000.IHC 1:50-200.
    密度
    靶标RNF114
    别名E3 ubiquitin-protein ligase RNF114;RING finger protein 114;RING-type E3 ubiquitin transferase RNF114;Zinc finger protein 228;Zinc finger protein 313;RNF114.
    背景说明E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn; participates in the regulation of many biological processes including cell cycle; apoptosis; osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Acts also as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation. Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C. This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence. May play a role in spermatogenesis.
    Swiss ProtQ9Y508
    Gene ID55905
    亚细胞定位Cytoplasm Nucleus
    免疫原Recombinant protein of human RNF114
    Public Immunogen Range1-200aa
    理论分子量21/26kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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