- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K110644P
- 2025年08月22日
- IHC
- Rabbit
- Mouse;Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human MBTPS2
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse;Human
- 抗原来源：
A synthetic peptide of human MBTPS2
- 目录编号：
51360
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:100-300.
- 靶点：
MBTPS2
- 抗体英文名：
Anti-MBTPS2 Polyclonal Antibody
- 抗体名：
S2P内肽酶抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-MBTPS2 Polyclonal Antibody |
| 中文名称 | S2P内肽酶抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Human |
| 预测交叉反应 | Cow(100%);Chimpanzee(92.9%);Hamster(100%) |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 密度 | |
| 靶标 | MBTPS2 |
| 别名 | BRESEK, Endopeptidase S2P, IFAP, KFSDX, MBTP2_HUMAN, MBTPS2, Membrane bound transcription factor site 2 protease, membrane-bound transcription factor peptidase, site 2, membrane-bound transcription factor protease, site 2, Membrane-bound transcription factor site-2 protease, S2P, S2P endopeptidase, Site 2 protease, SREBPs intramembrane protease, Sterol regulatory element-binding proteins intramembrane protease |
| 背景说明 | Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2 (PubMed:11163209, PubMed:10805775). Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached (PubMed:10805775, PubMed:27380894, PubMed:9659902). Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription (PubMed:10805775, PubMed:27380894, PubMed:9659902). Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B) (PubMed:11163209). Involved in intramembrane proteolysis during bone formation (PubMed:27380894). |
| Swiss Prot | O43462 |
| Gene ID | 51360 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human MBTPS2 |
| Public Immunogen Range | 5-55/519aa |
| 理论分子量 | 57kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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