- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K108975P
- 2025年08月22日
- WB
- Rabbit
- Rat;Mouse;Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human CELF-1
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Rat;Mouse;Human
- 抗原来源：
A synthetic peptide of human CELF-1
- 目录编号：
10658
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
WB 1:1000-3000.
- 靶点：
CELF1
- 抗体英文名：
Anti-CELF1 Polyclonal Antibody
- 抗体名：
胞苷尿苷鸟苷结合蛋白1抗体
- 规格：
20ul/50ul/100ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-CELF1 Polyclonal Antibody |
| 中文名称 | 胞苷尿苷鸟苷结合蛋白1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Rat;Mouse;Human |
| 预测交叉反应 | Chicken(100%);Chimpanzee(100%);Xenopus laevis(84.6%);Xenopus tropicalis(84.6%) |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | CELF1 |
| 别名 | 50 kDa Nuclear polyadenylated RNA binding protein;50 kDa nuclear polyadenylated RNA-binding protein;Bruno like 2;bruno like protein 2;Bruno-like protein 2;BRUNOL 2;BRUNOL2;CELF 1;CELF-1;celf1;CELF1 CUGBP, Elav like family member 1;CELF1_HUMAN;CUG BP and ETR 3 like factor 1;CUG BP;CUG BP1;CUG RNA binding protein;CUG triplet repeat RNA binding protein 1;CUG triplet repeat RNA-binding protein 1;CUG-BP;CUG-BP- and ETR-3-like factor 1;CUG-BP1;CUGBP 1;CUGBP and ETR3 like factor 1;CUGBP;CUGBP Elav like family member 1;CUGBP Elav-like family member 1;CUGBP1;Cytidine uridine guanosine binding protein 1;Deadenylation factor CUG BP;Deadenylation factor CUG-BP;Deadenylation factor CUGBP;EDEN BP;EDEN BP homolog;EDEN-BP;EDEN-BP homolog;embryo deadenylation element binding protein;embryo deadenylation element binding protein homolog;Embryo deadenylation element-binding protein homolog;hNab 50;hNab50;NAB 50;NAB50;NAPOR;Nuclear polyadenylated RNA binding protein 50 kD;Nuclear polyadenylated RNA binding protein;RNA binding protein BRUNOL 2;RNA binding protein BRUNOL2;RNA-binding protein BRUNOL-2; |
| 背景说明 | RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. Promotes exclusion of exon 11 of the INSR pre-mRNA. Inhibits, together with HNRNPH1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Increases translation and controls the choice of translation initiation codon of CEBPB mRNA. Increases mRNA translation of CEBPB in aging liver (By similarity). Increases translation of CDKN1A mRNA by antagonizing the repressive effect of CALR3. Mediates rapid cytoplasmic mRNA deadenylation. Recruits the deadenylase PARN to the poly(A) tail of EDEN-containing mRNAs to promote their deadenylation. Required for completion of spermatogenesis (By similarity). Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK and to Bruno response elements (BREs). Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. Binds to AU-rich sequences (AREs or EDEN-like) localized in the 3'-UTR of JUN and FOS mRNAs. Binds to the IR RNA. Binds to the 5'-region of CDKN1A and CEBPB mRNAs. Binds with the 5'-region of CEBPB mRNA in aging liver. May be a specific regulator of miRNA biogenesis. Binds to primary microRNA pri-MIR140 and, with CELF2, negatively regulates the processing to mature miRNA. |
| Swiss Prot | Q92879 |
| Gene ID | 10658 |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | A synthetic peptide of human CELF-1 |
| Public Immunogen Range | 1-51/486aa |
| 理论分子量 | 50/52/55kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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