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- 详细信息
- 技术资料
- 免疫原:
A synthetic peptide of human SGO1
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human
- 抗原来源:
A synthetic peptide of human SGO1
- 目录编号:
151648
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
IHC
- 浓度:
IHC 1:50-200.
- 靶点:
SGO1
- 抗体英文名:
Anti-SGO1 Polyclonal Antibody
- 抗体名:
乳腺癌NY BR 85抗原抗体
- 规格:
20ul/50ul/100ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 基本信息 | |
| 英文名称 | Anti-SGO1 Polyclonal Antibody |
| 中文名称 | 乳腺癌NY BR 85抗原抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | SGO1 |
| 别名 | hSgo 1;hSgo1;NY BR 85;Serologically defined breast cancer antigen NY BR 85;Serologically defined breast cancer antigen NY-BR-85;SGO 1;SGO;SGO L1;SGO1;SGOL 1;SGOL1;SGOL1_HUMAN;Shugoshin 1AB protein;Shugoshin 1CD protein;Shugoshin 1EFprotein;Shugoshin 1GH protein;Shugoshin 1KL protein;Shugoshin like 1 (S. pombe);Shugoshin like 1;Shugoshin-like 1; |
| 背景说明 | Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity. Involved in centromeric enrichment of AUKRB in prometaphase. |
| Swiss Prot | Q5FBB7 |
| Gene ID | 151648 |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | A synthetic peptide of human SGO1 |
| Public Immunogen Range | 385-435/561aa |
| 理论分子量 | 25/29/31/34/35/60/64kDa |
| EC | |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K108993P Anti-SGO1 Polyclonal Antibody
¥480 - 1600








