- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K110770P
- 2025年08月22日
- IHC
- Rabbit
- Human;Mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human EYA3
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse
- 抗原来源：
Recombinant protein of human EYA3
- 目录编号：
2140
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:50-200.
- 靶点：
EYA3
- 抗体英文名：
Anti-EYA3 Polyclonal Antibody
- 抗体名：
眼发育缺失蛋白同源物3抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-EYA3 Polyclonal Antibody |
| 中文名称 | 眼发育缺失蛋白同源物3抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 密度 | |
| 靶标 | EYA3 |
| 别名 | AI844637, DKFZp686C132, EYA3, EYA3_HUMAN, Eyes absent 3, Eyes absent 3 homolog (Drosophila), Eyes absent homolog 3, OTTMUSP00000010370, RP11-460I13.4, RP23-442A20.1 |
| 背景说明 | Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1 (PubMed:19234442, PubMed:19351884). Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity (By similarity). May be involved in development of the eye. |
| Swiss Prot | Q99504 |
| Gene ID | 2140 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human EYA3 |
| Public Immunogen Range | 1-350aa |
| 理论分子量 | 43/59/67kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K110770P Anti-EYA3 Polyclonal Antibody
￥480 - 1600
