Rabbit anti-Phospho-GSK3α/β(Ty
r279/216) Polyclonal Antibody【兔抗磷酸化GSK3α/β(Tyr279/216)多克隆抗体】- 询价
- Absin
- abs130960
- 上海
- 2025年08月26日
- Rabbit
- 见优宁维官网
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Rabbit anti-Phospho-GSK3α/β(Tyr279/216) Polyclonal mAb
- 抗体英文名：
Rabbit anti-Phospho-GSK3α/β(Tyr279/216) Polyclonal Antibody
- 靶点：
见优宁维官网
- 浓度：
1mg/ml
- 宿主：
Rabbit
- 适应物种：
见优宁维官网
- 保质期：
见优宁维官网
- 抗原来源：
见优宁维官网
- 级别：
优级
- 库存：
999
- 供应商：
Absin
- 标记物：
见优宁维官网
- 克隆性：
见优宁维官网
- 保存条件：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
- 免疫原：
A synthesized peptide derived from Human GSK3A(Accession P49840), corresponding to amino acid residues A267-E289.
- 规格：
100ug///50ug
别名：兔抗磷酸化GSK3α/β(Tyr279/216)多克隆抗体A synthesized peptide derived from Human GSK3A(Accession P49840), corresponding to amino acid residues A267-E289.WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:20000-1:40000Store at -20 °C for one year. Avoid repeated freeze/thaw cyclesElisa,IHC,WB,other见优宁维官网RabbitHuman;Mouse;Rat
克隆性：见优宁维官网
产品描述：
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
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文献和实验v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
loop of the kinase domain (Tyr279 in GSK3a, andTyr216 in GSK3b), which is absolutely required for kinase activity. Thirdly, phosphorylation of GSK3 at a conserved N-terminalserine residue inhibits its kinase activity. This phosphoserine actsas
Diego, CA); GSK-3α (Upstate, LakePlacid, NY); and b-actin (Sigma, St. Louis, MO). 7. Secondary antibodies: anti-mouse and anti-rabbit IgG conjugatedto horseradish peroxidase (Santa Cruz Biotechnology,Santa Cruz, CA). 8. Enhanced chemiluminescent
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