K114661P Anti-CMTM6 Polyclonal

Antibody

14 年钻石会员

免疫原：
A synthetic peptide of human CMTM6
亚型：
IgG
保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
克隆性：
Polyclonal Antibody
标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
适应物种：
Human
抗原来源：
A synthetic peptide of human CMTM6
目录编号：
54918
级别：
实验级别
库存：
现询
供应商：
北京索莱宝科技有限公司
宿主：
Rabbit
应用范围：
IHC
浓度：
IHC 1:50-200.
靶点：
CMTM6
抗体英文名：
Anti-CMTM6 Polyclonal Antibody
抗体名：
趋化素样因子超家族成员6
规格：
20ul/100ul/50ul

基本信息
英文名称	Anti-CMTM6 Polyclonal Antibody
中文名称	趋化素样因子超家族成员6
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Human
预测交叉反应	Chimpanzee(93.3%)
应用	IHC
稀释比例	IHC 1:50-200.
密度
靶标	CMTM6
别名	chemokine like factor super family 6; chemokine like factor superfamily 6; chemokine like factor superfamily member 6; Chemokine-like factor superfamily member 6; CKLF like MARVEL transmembrane domain containing 6; CKLF-like MARVEL transmembrane domain-containing protein 6; CKLF6_HUMAN; CKLFSF6; Cmtm6; Da2 17; LRRGT00102; PRO2219;
背景说明	Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Swiss Prot	Q9NX76
Gene ID	54918
亚细胞定位	Cell membrane Cytoplasm
免疫原	A synthetic peptide of human CMTM6
Public Immunogen Range	133-183/183aa
理论分子量	20kDa
EC
纯化方法	Affinity purification
储存液	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件	Store at -20℃. Avoid freeze / thaw cycles.

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