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K114712P Anti-PRKG1 Polyclonal

Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K114712P
  • 2025年08月20日
  • IHC
  • Rabbit
  • Mouse;Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant protein of human PRKG1

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Mouse;Human

    • 抗原来源

      Recombinant protein of human PRKG1

    • 目录编号

      5592

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC

    • 浓度

      IHC 1:50-200.

    • 靶点

      PRKG1

    • 抗体英文名

      Anti-PRKG1 Polyclonal Antibody

    • 抗体名

      cGMP依赖性蛋白激酶1

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-PRKG1 Polyclonal Antibody
    中文名称cGMP依赖性蛋白激酶1
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Mouse;Human
    预测交叉反应Rabbi;Bovine
    应用IHC
    稀释比例IHC 1:50-200.
    密度
    靶标PRKG1
    别名cGK 1; cGK1; cGKI alpha; cGKI; cGKI beta; cGMP-dependent protein kinase 1; cGMP-dependent protein kinase I; DKFZp686K042; FLJ36117; KGP1_HUMAN; KGPB; MGC71944; pkg; PRKG1; PRKG1B; PRKGR1A; PRKGR1B;
    背景说明Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
    Swiss ProtQ13976
    Gene ID5592
    亚细胞定位Cytoplasm
    免疫原Recombinant protein of human PRKG1
    Public Immunogen Range330-680aa
    理论分子量44/76/79kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

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