- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K114887P
- 2025年08月20日
- IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human TPPP
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
Recombinant protein of human TPPP
- 目录编号：
11076
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:50-200.
- 靶点：
TPPP
- 抗体英文名：
Anti-TPPP Polyclonal Antibody
- 抗体名：
微管蛋白聚合促进蛋白
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-TPPP Polyclonal Antibody |
| 中文名称 | 微管蛋白聚合促进蛋白 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Bovine |
| 应用 | WB;IHC |
| 稀释比例 | WB 1:1000-3000.IHC 1:50-200. |
| 密度 | |
| 靶标 | TPPP |
| 别名 | 25 brain specific protein;25 brain-specific protein;Brain specific protein p25 alpha;Glycogen synthase kinase 3 (GSK3) inhibitor p24;OTTHUMP00000161630;p24;p25;p25-alpha;p25alpha;TPPP;TPPP/p25;TPPP_HUMAN;TPPP1;Tubulin polymerization promoting protein;Tubulin polymerization-promoting protein; |
| 背景说明 | Regulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath. Acts as a microtubule nucleation factor in oligodendrocytes: specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, and promotes microtubule nucleation, an important step for elongation of the myelin sheath. Required for both uniform polarized growth of distal microtubules as well as directing the branching of proximal processes. Shows magnesium-dependent GTPase activity;the role of the GTPase activity is unclear. In addition to microtubule nucleation activity, also involved in microtubule bundling and stabilization of existing microtubules, thereby maintaining the integrity of the microtubule network. Regulates microtubule dynamics by promoting tubulin acetylation: acts by inhibiting the tubulin deacetylase activity of HDAC6. Also regulates cell migration: phosphorylation by ROCK1 inhibits interaction with HDAC6, resulting in decreased acetylation of tubulin and increased cell motility. Plays a role in cell proliferation by regulating the G1/S-phase transition. Involved in astral microtubule organization and mitotic spindle orientation during early stage of mitosis;this process is regulated by phosphorylation by LIMK2. |
| Swiss Prot | O94811 |
| Gene ID | 11076 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human TPPP |
| Public Immunogen Range | 1-220aa |
| 理论分子量 | 24kDa |
| 实际分子量 | 24kDa |
| EC | |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 储存液 | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K114887P Anti-TPPP Polyclonal Antibody
￥480 - 1600
