- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K109584P
- 2025年08月20日
- IHC;ELISA
- Rabbit
- Human;Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human CHI3L1
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse
- 抗原来源：
Recombinant protein of human CHI3L1
- 目录编号：
1116
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC;ELISA
- 浓度：
IHC 1:50-200. ELISA 1:2000-20000.
- 靶点：
CHI3L1
- 抗体英文名：
Anti-CHI3L1 Polyclonal Antibody
- 抗体名：
几丁质酶3样蛋白1抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-CHI3L1 Polyclonal Antibody |
| 中文名称 | 几丁质酶3样蛋白1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Rat;Mouse |
| 应用 | WB;IHC;ELISA |
| 稀释比例 | WB 1:2000-5000. IHC 1:50-200. ELISA 1:2000-20000. |
| 密度 | |
| 靶标 | CHI3L1 |
| 别名 | 39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP-39, CGP39, CH3L1_HUMAN, CHI3L1, chitinase 3 like 1 (cartilage glycoprotein 39), chitinase 3 like 1, Chitinase 3 like protein 1 precursor, chitinase, Chitinase-3-like protein 1, Chondrocyte protein YKL40, GP 39, GP-39, GP39, HC gp39, HCGP 3P, hCGP-39, HCgp39, YKL 40, YKL-40, YKL40, YYL 40 |
| 背景说明 | Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. |
| Swiss Prot | P36222 |
| Gene ID | 1116 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human CHI3L1 |
| Public Immunogen Range | 1-383aa |
| 理论分子量 | 43kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
成员:Yanna Song, Wei Jiang, Shabbir Khan Afridi, Tongtong Wang, Fan Zhu, Huiming Xu, Faisal Hayat Nazir, Chunxin Liu, Yuge Wang, Youming Long, Yu-Wen Alvin Huang, Wei Qiu, Changyong Tang
论文因子:7.5 发表期刊:Cell Reports pmid:38733586
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation
成员:Wei Jiang, Fan Zhu, Huiming Xu, Li Xu, Haoyang Li, Xin Yang, Shabbir Khan Afridi, Shuiqing Lai, Xiusheng Qiu, Chunxin Liu, Huilu Li, Youming Long, Yuge Wang, Kevin Connolly, Jack A. Elias, Chun Geun Lee, Yaxiong Cui, Yu-Wen Alvin Huang, Wei Qiu, Changyong
论文因子:13.6 发表期刊:Science Advances pmid:37756391
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