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- 详细信息
- 技术资料
- 保存条件:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期:
12个月
- 英文名:
Recombinant human IDE Protein with C-terminal 10×His tag
- 库存:
In Stock
- 供应商:
缔码生物(武汉)科技有限公司
- 规格:
10μg/50μg/100μg
| 规格: | 10μg | 产品价格: | ¥706.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥2500.0 |
| 规格: | 100μg | 产品价格: | ¥3699.0 |
| 产品类型 | ECD Proteins |
|---|---|
| 靶点 | IDE |
| Uniprot ID | P14735 |
| 别名 | INSULYSIN |
| 背景 | This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] |
| 产品英文名称 | Recombinant human IDE Protein with C-terminal 10×His tag |
| 分子结构 | IDE(Met1-Leu1019) 10×His tag |
| 分子量 | The protein has a predicted molecular mass of 119.3 kDa after removal of the signal peptide. |
| 纯度 | The purity of the protein is greater than 80% as determined by SDS-PAGE and Coomassie blue staining. |
| 标签 | C-10×His tag |
| 有无偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 货期 | In Stock |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 应用范围 | Research use only |

Figure 1. Human IDE Protein, His Tag on SDS-PAGE under reducing condition.
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人IDE重组蛋白/Human IDE Protein, His Tag
¥706 - 3699






