- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K111307P
- 2025年08月13日
- IHC;ELISA
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 技术资料
- 免疫原：
A synthetic peptide of human ACO1
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse;Rat
- 抗原来源：
A synthetic peptide of human ACO1
- 目录编号：
48
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC;ELISA
- 浓度：
IHC 1:100-300. ELISA 1:20000-200000.
- 靶点：
ACO1
- 抗体英文名：
Anti-ACO1 Polyclonal Antibody
- 抗体名：
铁调节蛋白1抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-ACO1 Polyclonal Antibody |
| 中文名称 | 铁调节蛋白1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Rat;Human |
| 预测交叉反应 | Cow(93.3%);Rabbit(100%);Chicken(93.3%) |
| 应用 | ELISA;IHC;WB;IP |
| 稀释比例 | WB 1:1000-3000. IHC 1:100-300. IP 1:50-500. ELISA 1:20000-200000. |
| 密度 | |
| 靶标 | ACO1 |
| 别名 | ACONS,HEL60,IREB1,IREBP,IREBP1,IRP1 |
| 背景说明 | The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants. |
| Swiss Prot | P21399 |
| Gene ID | 48 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human ACO1 |
| Public Immunogen Range | 130-180/889aa |
| 理论分子量 | 98kDa |
| EC | |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K111307P Anti-ACO1 Polyclonal Antibody
￥480 - 1600
