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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human THOC5
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Rat;Human;Mouse
- 抗原来源:
Recombinant protein of human THOC5
- 目录编号:
8563
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
WB 1:1000-3000.
- 靶点:
THOC5
- 抗体英文名:
Anti-THOC5 Polyclonal Antibody
- 抗体名:
THO 复合体 5抗体
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-THOC5 Polyclonal Antibody |
| 中文名称 | THO 复合体 5抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Rat;Human;Mouse |
| 预测交叉反应 | Bovine;Fruit fly;Chicken |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | THOC5 |
| 别名 | C22orf19; Chromosome 22 open reading frame 19; Fmip; Fms interacting protein; fSAP79; Functional spliceosome-associated protein 79; hTREX90; KIAA0983; LOC400922; NF2/meningioma region protein pK1.3; PK1.3; Placental protein 39.2; PP39.2; THO complex 5; THO complex subunit 5; THO complex subunit 5 homolog; thoc5; THOC5_HUMAN; |
| 背景说明 | Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC5 in conjunction with ALYREF/THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in transcription elongation and genome stability. Involved in alternative polyadenylation site choice by recruiting CPSF6 to 5' region of target genes; probably mediates association of the TREX and CFIm complexes. |
| Swiss Prot | Q13769 |
| Gene ID | 8563 |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | Recombinant protein of human THOC5 |
| Public Immunogen Range | 1-350aa |
| 理论分子量 | 79kDa |
| 实际分子量 | 79kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K112634P Anti-THOC5 Polyclonal Antibody
¥480 - 1600








