- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K112891P
- 2025年08月13日
- WB
- Rabbit
- Human;Mouse
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- 详细信息
- 技术资料
- 免疫原：
Recombinant protein of human SYNE2
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human;Mouse
- 抗原来源：
Recombinant protein of human SYNE2
- 目录编号：
23224
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
WB 1:1000-3000.
- 靶点：
SYNE2
- 抗体英文名：
Anti-SYNE2 Polyclonal Antibody
- 抗体名：
含spectrin重复序列蛋白抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-SYNE2 Polyclonal Antibody |
| 中文名称 | 含spectrin重复序列蛋白抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | SYNE2 |
| 别名 | DKFZP434H2235;DKFZp686E01115;DKFZp686H1931;EDMD5;FLJ46790;KIAA1011FLJ11014;nesprin 2;Nesprin-2;NUAFLJ43727;NUANCEFLJ45710;Nuclear envelope spectrin repeat protein 2;Nucleus and actin connecting element protein;polytrophin;Protein NUANCE;spectrin repeat containing, nuclear envelope 2;Synaptic nuclear envelope protein 2;synaptic nuclei expressed gene 2;SYNE-2;TROPH; |
| 背景说明 | Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. May be involved in nucleus-centrosome attachment. During interkinetic nuclear migration (INM) at G2 phase and nuclear migration in neural progenitors its LINC complex association with SUN1/2 and probable association with cytoplasmic dynein-dynactin motor complexes functions to pull the nucleus toward the centrosome; SYNE1 and SYNE2 may act redundantly. During INM at G1 phase mediates respective LINC complex association with kinesin to push the nucleus away from the centrosome. Involved in nuclear migration in retinal photoreceptor progenitors. Required for centrosome migration to the apical cell surface during early ciliogenesis. |
| Swiss Prot | Q8WXH0 |
| Gene ID | 23224 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human SYNE2 |
| Public Immunogen Range | 1-286aa |
| 理论分子量 | 30/32/48/51/61/62/76/87/98/119/337/796/799kDa |
| 实际分子量 | 110kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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K112891P Anti-SYNE2 Polyclonal Antibody
￥480 - 1600
