- ￥480 - 1600
- Solarbio|ActivAb
- 北京
- K112983P
- 2025年08月13日
- IHC
- Rabbit
- Mouse;Human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant protein of human TRPC4AP
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse;Human
- 抗原来源：
Recombinant protein of human TRPC4AP
- 目录编号：
26133
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
IHC
- 浓度：
IHC 1:25-100.
- 靶点：
TRPC4AP
- 抗体英文名：
Anti-TRPC4AP Polyclonal Antibody
- 抗体名：
瞬时受体电位阳离子通道C亚家族成员4相关蛋白抗体
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-TRPC4AP Polyclonal Antibody |
| 中文名称 | 瞬时受体电位阳离子通道C亚家族成员4相关蛋白抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse;Human |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 密度 | |
| 靶标 | TRPC4AP |
| 别名 | C20orf188; TRPC4AP; Chromosome 20 open reading frame 188; Protein TAP1; Protein TRUSS; Short transient receptor potential channel 4 associated protein; Short transient receptor potential channel 4-associated protein; TAP1 protein; TNF receptor ubiquitous scaffolding/signaling protein; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP_HUMAN; Transient receptor potential cation channel, subfamily C, member 4 associated protein; Trp4 associated protein; Trp4-associated protein; Trpc4 associated protein; Trpc4-associated protein; TRPC4AP; TRRP4AP; TRUSS; Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein; |
| 背景说明 | Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control (PubMed:20551172, PubMed:29779948). The DCX(TRPC4AP) complex specifically mediates the polyubiquitination and subsequent degradation of MYC as part of the DesCEND (destruction via C-end degrons) pathway (PubMed:20551172, PubMed:29779948). The DesCEND (destruction via C-end degrons) pathway recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948). The DCX(TRPC4AP) complex specifically recognizes proteins with an arginine at the minus 3 position (R-3 motif) at the C-terminus, such as MYC, leading to their ubiquitination and degradation (PubMed:29779948). Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome (By similarity). Involved in JNK activation via its interaction with TRAF2 (By similarity). Also involved in elevation of endoplasmic reticulum Ca2+ storage reduction in response to CHRM1 (By similarity). |
| Swiss Prot | Q8TEL6 |
| Gene ID | 26133 |
| 亚细胞定位 | Cell membrane Cytoplasm |
| 免疫原 | Recombinant protein of human TRPC4AP |
| Public Immunogen Range | 1-350aa |
| 理论分子量 | 60/90/91kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
技术资料暂无技术资料 索取技术资料
