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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the N-terminal region of human MEK2.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0658
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
P36507
- 抗体英文名:
Anti-MEK2 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-MEK2 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
MEK2 (Mitogen-Activated Protein Kinase Kinase 2), also known as MAP2K2, is a dual-specificity kinase that plays a pivotal role in the RAS/MAPK signaling pathway. It functions by phosphorylating and activating the extracellular signal-regulated kinases ERK1 and ERK2, which are critical for regulating cellular processes such as proliferation, differentiation, and survival. MEK2 is activated through phosphorylation by upstream kinases like RAF, enabling it to transmit mitogenic and stress signals from the cell membrane to the nucleus. Genetic mutations in the MAP2K2 gene have been associated with developmental disorders, including cardiofaciocutaneous syndrome, characterized by heart defects, distinctive facial features, and cognitive impairments. Due to its central role in cell signaling, MEK2 is also a target of interest in cancer research and therapeutic development.
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文献和实验该产品被引用文献
Crews, C.M. et al. (1992) Science 258, 478-480.
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Anti-MEK2 Recombinant Rabbit Monoclonal Ab
¥860





