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Anti-MLL2 / KMT2D Recombinant

Rabbit Monoclonal Ab
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  • ¥860
  • Elucigen Biosciences
  • ERB0563
  • 2025年08月13日
  • ICC, IHC, WB
  • Rabbit
  • Human, Mouse (predicted)
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Synthetic peptide corresponding to the C-terminal region of human MLL2.

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      -20°C

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      Human, Mouse (predicted)

    • 保质期

      12 months from the shipping date of the product.

    • 抗原来源

      Human

    • 目录编号

      ERB0563

    • 级别

      Primary Antibodies

    • 库存

      Available

    • 供应商

      Elucigen Biosciences

    • 宿主

      Rabbit

    • 应用范围

      ICC, IHC, WB

    • 浓度

      0.5 mg/mL

    • 靶点

      O14686

    • 抗体英文名

      Anti-MLL2 / KMT2D Recombinant Rabbit Monoclonal Ab

    • 抗体名

      Anti-MLL2 / KMT2D Recombinant Rabbit Monoclonal Ab

    • 规格

      25μg/100μg/500μg

    规格:25μg产品价格:¥860.0
    规格:100μg产品价格:询价
    规格:500μg产品价格:询价
    MLL2, also known as KMT2D (Lysine Methyltransferase 2D), is a large nuclear protein that functions as a histone methyltransferase, specifically catalyzing the mono- and di-methylation of histone H3 at lysine 4 (H3K4me1/2). This modification is associated with transcriptionally active chromatin and plays a vital role in regulating gene expression, particularly at enhancer regions. KMT2D is a key component of the COMPASS-like (Complex of Proteins Associated with Set1) chromatin-modifying complex. It is critical for various biological processes including embryonic development, cell differentiation, and maintenance of stem cell identity. Due to its epigenetic regulatory functions, KMT2D has become a major focus in the study of developmental disorders, such as Kabuki syndrome, and a wide range of cancers, where it is frequently mutated or dysregulated.

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    图标文献和实验
    该产品被引用文献
    Shilatifard, A. (2008) Curr Opin Cell Biol 20, 341-8.
    相关实验
    • Clonality - X Chromosome Inactivation Assay

      and can assist in interpretation of allele patterns. 4. References Allen RC, Zoghbi HY, Moseley AB, Rosenblatt HM, Belmont JW. Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome

    • 【求助】抗体名称Ab-33是什么意思?

      around the phosphorylation site of serine 33 (L-D-SP-G-I)。 http://www.genscript.com/product_001/rec_antibody/code/A00584/category/antibody/Rabbit_Anti_beta-Catenin_Ab-33_polyclonal.html bettyzyj http://www.signalwayantibody.com/resurgam/uppdf/21211.pdf

    • Notes on Making Rat x Y3 Monoclonal Antibody Producing Hybridomas

      throughout the procedure. d) Plate the entire fusion out in just 120 x 1ml cultures in 6 x 'Linbro' 24 well plates, using DMEM + 20% FCS (containing penniclin + streptomicin, Na pyruvate and glutamine). e) DO NOT use Isoves medium (IMDM) as this will encourage

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    文献支持
    Anti-MLL2 / KMT2D Recombinant Rabbit Monoclonal Ab
    ¥860