- ￥860
- Elucigen Biosciences
- ERB0508
- 2025年08月13日
- ICC, IHC, WB, Flow
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide corresponding to the C-terminal region of human CDK1.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
-20°C
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
ERB0508
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
Elucigen Biosciences
- 宿主：
Rabbit
- 应用范围：
ICC, IHC, WB, Flow
- 浓度：
0.5 mg/mL
- 靶点：
P06493
- 抗体英文名：
Anti-CDK1 / CDC2 Recombinant Rabbit Monoclonal Ab
- 抗体名：
Anti-CDK1 / CDC2 Recombinant Rabbit Monoclonal Ab
- 规格：
25μg/100μg/500μg
| 规格： | 25μg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 100μg | 产品价格： | 询价 |
| 规格： | 500μg | 产品价格： | 询价 |
CDK1 (Cyclin-Dependent Kinase 1), also known as CDC2, is a crucial serine/threonine kinase that plays a central role in regulating the cell cycle, particularly the transition from G2 phase to M phase (mitosis). CDK1 functions in complex with cyclins, particularly Cyclin B, to form the Maturation Promoting Factor (MPF), which is essential for the initiation of mitosis. The activity of CDK1 is tightly regulated through phosphorylation and dephosphorylation events, ensuring proper cell division and genomic stability. Dysregulation of CDK1 activity can lead to cell cycle defects, contributing to diseases such as cancer, where uncontrolled cell division occurs. CDK1 is also involved in other processes beyond mitosis, including DNA damage repair, apoptosis, and cell differentiation. It remains a key target in cancer research, with inhibitors of CDK1 being explored as potential therapeutic agents.
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文献和实验该产品被引用文献
Norbury, C. et al. (1991) EMBO J 10, 3321-9.
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Anti-CDK1 / CDC2 Recombinant Rabbit Monoclonal Ab
￥860
