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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the C-terminal region of human Podocin.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0615
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q9NP85
- 抗体英文名:
Anti-Podocin Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-Podocin Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Podocin is a kidney-specific integral membrane protein encoded by the NPHS2 gene. It is predominantly expressed in podocytes—specialized epithelial cells lining the glomerular capillaries—and is a critical component of the slit diaphragm, a structure essential for the kidney's filtration barrier. Podocin interacts with proteins such as nephrin and CD2AP, contributing to the assembly and maintenance of the slit diaphragm complex. Mutations in the NPHS2 gene can disrupt podocin function, leading to conditions like steroid-resistant nephrotic syndrome, characterized by proteinuria and progressive kidney disease.
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文献和实验该产品被引用文献
Liang, L. et al. (2024) FASEB J. 38(10):e23662.
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Anti-Podocin Recombinant Rabbit Monoclonal Ab
¥860






