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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide corresponding to the N-terminal region of human NLRP3.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
ERB0492
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Rabbit
- 应用范围:
ICC, IHC, WB
- 浓度:
0.5 mg/mL
- 靶点:
Q96P20
- 抗体英文名:
Anti-NLRP3 Recombinant Rabbit Monoclonal Ab
- 抗体名:
Anti-NLRP3 Recombinant Rabbit Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
NLRP3 is a key protein involved in the immune response and inflammation. It is a member of the NLRP (NOD-like receptor family), which plays a critical role in detecting cellular stress and pathogen-associated signals. NLRP3 functions as an inflammasome component, a multiprotein complex that activates caspase-1 and leads to the production of pro-inflammatory cytokines, such as IL-1β and IL-18, in response to infections, injury, or metabolic stress. Dysregulation of NLRP3 inflammasome activation is linked to various inflammatory diseases, including autoimmune disorders, gout, cardiovascular diseases, and neurodegenerative conditions like Alzheimer’s disease. Research into NLRP3 is critical for understanding its role in immunity, inflammation, and disease pathogenesis, with potential therapeutic implications for treating inflammation-related disorders.
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文献和实验该产品被引用文献
Elinav, E. et al. (2011) Immunity 34, 665-79.
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Anti-NLRP3 Recombinant Rabbit Monoclonal Ab
¥860





