CAS#6340-52-9 | Methyl 6-deoxy

眼看它就要封神了...Science 报道烟酰胺可增强胰岛素敏感性、促进肌肉重塑

烟酰胺腺嘌呤二核苷酸（NAD+）在多种生物过程的调节中至关重要，是 NAD + 代谢相关酶的底物。在啮齿类动物中，肝脏、脂肪组织和骨骼肌中不充分的 NAD + 生物合成会导致肥胖和衰老相关代谢异常的疾病，包括胰岛素耐受性、β 细胞功能障碍和肝脏脂肪变性。NAD + 生物合成的主要途径包括烟酰胺转化为烟酰胺单核苷酸（nicotinamide mononucleotide，NMN），随后 NMN 转化为 NAD+。NMN 的产生是哺乳动物 NAD + 生物合成的关键限速因子。 已有研究发现高脂

Preparation of 2′‐Deoxy‐2′‐Methylseleno‐Modified Phosphoramidites and RNA

of nucleic acids with selenium is a useful approach to facilitate phase determination during three?dimensional structural analysis by X?ray crystallography. This unit describes (1) the synthesis and characterization of 2??deoxy?2??methylseleno (2??Se?methyl

Structural Characterization of the Heteroxylans from Poplar and Switchgrass

Heteroxylans are polysaccharides with a backbone composed of 1,4-linked β-d -xylosyl residues. In hardwoods some of these xylosyl residues are substituted at O -2 with 4-O -methyl α-d -glucuronic and occasionally with α-d -glucuronic acid