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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期:
1 year
- 英文名:
Recombinant Mouse RNASEH2 Protein, N-His
- 库存:
999
- 供应商:
abinScience
- 规格:
100ug

| Product name | Recombinant Mouse RNASEH2 Protein, N-His |
|---|---|
| Catalog No. | MF989012 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | Q9CWY8 |
| Reconstitution | Reconstitute in sterile water for a stock solution. |
| Alternative Names | Ribonuclease H2 subunit A, RNase H2 subunit A, EC:3.1.26.4, Ribonuclease HI large subunit, RNase HI large subunit, Ribonuclease HI subunit A, Rnaseh2a |
| Species | Mus musculus (Mouse) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
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Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• Clinical and molecular phenotype of Aicardi-Goutieres syndrome., PMID:17846997
• RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases., PMID:19034401
• Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition., PMID:29315404
• Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia., PMID:35500843
• Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea., PMID:28373277
• High Flexibility of RNaseH2 Catalytic Activity with Respect to Non-Canonical DNA Structures., PMID:34068992
• AGS, SLE, and RNASEH2 mutations: translating insights into therapeutic advances., PMID:25500879
• Second generation lethality in RNAseH2a knockout zebrafish., PMID:39217460
• Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition., PMID:30532030
Recombinant DNA Engineering, Or Cloning Genes In Plasmids
and thus fusion proteins. For example there might be sequence for a fluorescent protein such as GFP or a peptide tag such as HA upstream of MCS (and downstream of promoter) so that an insert in frame will lead to the generation of a fusion protein, an N-terminal
depends on product and its function. N-terminal sequencing revealed that the purified rBoNTC(Hc )-N is missing the first eight amino acids of the N-terminus of the protein, whereas the purified rBoNTC(Hc )-C protein is intact. After a mouse bioassay test
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
, A., Sopko, R., McCartney, R.R., Schmidt, M.C., Rachidi, N., Lee, S.J., Mah, A.S., Meng, L., Stark, M.J., Stern, D.F., De Virgilio, C., Tyers, M., Andrews, B., Gerstein, M., Schweitzer, B., Predki, P.F., and Snyder, M. 2005. Global analysis of protein
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