- ￥940 - 3290
- Solarbio|ActivAb
- 北京
- CLP1720
- 2025年07月29日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 保质期：
Store at -20℃，2 years.(Avoid freeze/thaw cycles)
- 英文名：
Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
10mg/5mg/1mg
| 规格： | 10mg | 产品价格： | ￥3290.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥2350.0 |
| 规格： | 1mg | 产品价格： | ￥940.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.149155-45-3 |
| 单字母序列 | KRREILSRRPSYR |
| 三字母序列 | Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg |
| 分子式 | C73H129N29O19 |
| 分子量 | 1717.01 |
| 纯度 | ≥95% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 溶解性 | H2O：100 mg/mL; *超声助溶; |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 底物和酶抑制剂(Substrate and Enzyme Inhibitors) |
| 规格 | CREBtide 是一种合成的含 13 个氨基酸的肽，作为一种 PKA 底物。CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA substrate. |
| In Vitro | delta-CREB is a spliced variant of cAMP response element binding protein (CREB). CREBtide (KRREILSRRPSYR), a synthetic peptide based on the phosphorylation sequence in delta-CREB. delta-CREB and CREBtide are tested as substrates of cAMP-dependent protein kinase (cAK). The apparent Km of CREBtide phosphorylation by cAK is 3.9 μM, which is 10-fold lower than that of Kemptide (Km=39 μM), the synthetic peptide substrate most often employed for cAK measurement. The Vmax values are 12.4 mumol/(min.mg) for CREBtide and 9.8 mumol/(min.mg) for Kemptide. The apparent Km of CREBtide phosphorylation by cGMP-dependent protein kinase (cGK) is 2.9 μM and the Vmax value is 3.2 mumol/(min.mg). Both delta-CREB and CREBtide are phosphorylated at a much slower rate by cGK as compared with cAK, implying that the high cAK/cGK specificity exhibits by delta-CREB is retained by the peptide. |
| 单位 | 瓶 |
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￥940 - 3290
