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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Neutrophil gelatinase-associated lipocalin;NGAL;25 kDa alpha-2-microglobulin-related subunit of MMP-9;Lipocalin-2;Oncogene 24p3;Siderocalin LCN2;p25;HNL;NGAL |
| 外观(性状) | Supplied as a 0.2 μm filtered solution of PBS, 50% glycerol,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 运输条件 | 干冰运输 |
| 背景说明 | LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis,innate immunity and renal development.LCN2 binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA),a siderophore that shares structural similarities with bacterial enterobactin,and delivers or removes iron from the cell,depending on the context.LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis,while iron-free form decreases intracellular iron levels,inducing expression of the proapoptotic protein BCL2L11/BIM,resulting in apoptosis.LCN2 is involved in innate immunity,possibly by sequestrating iron,leading to limit bacterial growth. |
| 来源 | Human Cells |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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