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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Low Affinity Immunoglobulin Gamma Fc Region Receptor IV;FcgR4;CD16-2 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Fcgr4,also known as CD16-2,is one of the receptors for Fc region of IgG which involve in immune responses.Fcgr4 mainly functions in cellular response to lipopolysaccharide,NK T cell proliferation,regulation of sensory perception of pain,wound healing etc.Three groups are included for Fc γ receptors (FcR),and they are Fc γ RI (CD64),Fc γ RII (CD32),and Fc γ RIII (CD16).Among these,CD64 possess high affinity even for monomeric IgG,while CD32 and CD16 display a relative lower affinity for IgG.Genes encodes these receptors are diverse differing by species and cell types.The aggregation of FcR having immunoreceptor tyrosine-based activation motifs (ITAMs) activates sequentially src family tyrosine kinases and syk family tyrosine kinases that connect transduced signals to common activation pathways shared with other receptors.FcR with ITAMs elicit cell activation,endocytosis,and phagocytosis.Fcgr4 belongs to Fc γ RIII (CD16) group. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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