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- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥21120.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥14784.0 |
| 规格: | 50ug | 产品价格: | ¥2600.0 |
| 规格: | 10ug | 产品价格: | ¥988.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Glypican-1;GPC1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling.Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence,a 507 aa mature segment,and a 28 aa C-terminal prosegment.There are two potential N-linked and four potential O-linked sites for glycosylation or glycanation.There are potentially two heparan sulfate (HS) modifications on GPC1 that could contribute to a native molecular weight of approximately 200 kDa.Mature human GPC1 shares 91% aa identity with mature mouse GPC1.Cells known to express GPC1 include neurons,smooth and skeletal muscle cells,keratinocytes,osteoblasts,Schwann cells,immature dendritic cells,and tumor,plus tumorassociated vascular endothelial cells.The function of GPC1 is complex and varied.As a proteoglycan,it appears to make use of its HS adduct to impact select growth factor activity.This is accomplished by having juxtramembrane HS attachment sites,and a flexible,GPI-linkage. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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