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P01087 Recombinant Human Glypi

can-1/GPC1 细胞因子/蛋白
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  • ¥988 - 21120
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  • P01087
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Glypican-1;GPC1
    外观(性状)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    纯度≥95% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling.Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence,a 507 aa mature segment,and a 28 aa C-terminal prosegment.There are two potential N-linked and four potential O-linked sites for glycosylation or glycanation.There are potentially two heparan sulfate (HS) modifications on GPC1 that could contribute to a native molecular weight of approximately 200 kDa.Mature human GPC1 shares 91% aa identity with mature mouse GPC1.Cells known to express GPC1 include neurons,smooth and skeletal muscle cells,keratinocytes,osteoblasts,Schwann cells,immature dendritic cells,and tumor,plus tumorassociated vascular endothelial cells.The function of GPC1 is complex and varied.As a proteoglycan,it appears to make use of its HS adduct to impact select growth factor activity.This is accomplished by having juxtramembrane HS attachment sites,and a flexible,GPI-linkage.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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