P00873 Recombinant Mouse TNFRS
F11B/Osteoprotegerin/OPG/Tumor Necrosis Factor Receptor Superfamily Member 11B 细胞因子/蛋白- ￥936 - 15360
- Solarbio
- P00873
- 北京
- 2025年07月25日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥15360.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥10752.0 |
| 规格： | 50ug | 产品价格： | ￥2600.0 |
| 规格： | 10ug | 产品价格： | ￥936.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Tumor necrosis factor receptor superfamily member 11B;Osteoclastogenesis inhibitory factor;Osteoprotegerin;Tnfrsf11b;Ocif;Opg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Osteoprotegerin (OPG，Tnfrsf11b) is a secreted protein that regulates bone density.OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells，fibroblasts and endothelial cells.Regulation of its expression by estrogen，parathyroid hormone and cytokines is complex and changes with age.OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.TRAIL decreases the release of OPG from cells that express it，while OPG inhibits TRAIL-induced apoptosis.Expression of RANK L on the cell surface，and thus its ability to stimulate osteoclastogenesis，is regulated by OPG by intracellular and extracellular mechanisms.Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B.It may also play a role in preventing arterial calcification. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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